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Fungal keratitis or keratomycosis

This refers to an infective process of the cornea caused by any of the multiple  pathologic fungi capable of invading the ocular surface. It is typically slow and relentless.  Signs: ⮚ Corneal lesions with white/gray infiltrate and feathery borders. ⮚ Satellite lesions with a hypopyon.  ⮚ Conjunctival injection as well as purulent secretions.   Symptoms:  o …

This refers to an infective process of the cornea caused by any of the multiple  pathologic fungi capable of invading the ocular surface. It is typically slow and relentless. 

Signs:

⮚ Corneal lesions with white/gray infiltrate and feathery borders. ⮚ Satellite lesions with a hypopyon. 

⮚ Conjunctival injection as well as purulent secretions.  

Symptoms: 

o Blurred vision  

o Redness 

o Tearing 

o Photophobia 

o Pain 

o Foreign body sensation 

o Secretions 

In some cases the lesion are rather indolent which help to delay the diagnosis and  hence delay the treatment. Suspicion should be high in cases of trauma with  vegetable matter.  

Treatment  

Fungal ulcers are inherently difficult to treat. Antifungal drops but only a polyene,  natamycin 5%, Furthermore, the complexity of the disease and possible visually  devastating outcomes require a rather aggressive approach to its treatment.  

Voriconazole, a triazole antifungal agent derived from fluconazole, can be used  either topically at 1% dilution, orally at 400 mg twice a day  

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